Ilexhainanoside D
Ilexhainanoside D
CAS: 1137648-52-2
Molecular Formula: C36H56O11
Ilexhainanoside D - Names and Identifiers
| Name | Ilexhainanoside D |
| Synonyms | Ilexhainanoside D Olean-12-ene-23,28-dioic acid, 3,19-dihydroxy-, 28-β-D-glucopyranosyl ester, (3β,4β,19α)- |
| CAS | 1137648-52-2 |
Ilexhainanoside D - Physico-chemical Properties
| Molecular Formula | C36H56O11 |
| Molar Mass | 664.83 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Boling Point | 788.1±60.0 °C(Predicted) |
| pKa | 4.47±0.70(Predicted) |
| Storage Condition | -20℃ |
| In vivo study | The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240 mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes / Bacteroidetes , reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia . The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines. |
Ilexhainanoside D - Reference Information
| biological activity | Ilexhainanoside D from Ilex hainanensis Merr. The main triterpenoid saponin extracted in, Ilexhainanoside D and Ilexsaponin A1 have an anti-inflammatory effect after combined use. |
Last Update：2024-04-09 21:32:09
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Mobile: 18021002903
QQ: 3008007409
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